1970
Marine David Haskell is killed. At some point in the future, his identity is assumed by an intelligence agent involved in the alien conspiracy. (8x08 Per Manum)
Circa 1970
Future FBI Deputy Director Kersh is an Air Force pilot in Vietnam, often flying his jets just feet above the treetops. (8x01 Within)
Walter Skinner enlists in the Marines on his 18th birthday. (3x21 Avatar)
March 13, 1971
Birthdate of Monica Reyes, based on the birthday of actress Annabeth Gish.
May 2, 1972
J. Edgar Hoover dies. (Historical)
November 20, 1972
Carl Sagan, Philip Morrison, Ashley Montagu and other scientists participate in a symposium sponsored by NASA on intelligent life in the universe. (4x20 Gethsemane)
1973
Circa this period, the Scully family lives in California, while William Scully is stationed at Miramar Naval Air Station, San Diego, Dana is vaccinated for smallpox. (3x09 Nisei & 3x10 731)
The Adam and Eve clones in the Litchfield Experiment become homicidal, This may be about the time that Eve 8 escapes, Eve 7 enters college, with the goal of completing degrees in genetics and medicine. (1x11 Eve) 
October 13, 1973
State Department staff members have learned that the aliens encountered at Roswell are planning to colonize Earth in a process that will kill all humans. (6x12 One Son)
Bill Mulder is the only dissenting vote. When the aliens provide an alien fetus to the Consortium, providing DNA with which to develop the hybrids, Mulder devises a plan to use the DNA to create a vaccine, so that the entire human population might be saved.
When the humans agree to help the Colonists, the aliens demand that each give up a child or other loved one into the custody of the colonists, with the promise that they will be returned when the colonization begins.
A dark, shadowy organization of people, mostly men, the Consortium eventually includes members from many countries.
As time goes by, and no vaccine is developed, some members of the Consortium come to believe that slavery for the human race is better than death. 
November 1973
In 1997, Mulder experiences a series of flashbacks to events in his family's summer cottage in Rhode Island during which Bill Mulder apparently tells his wife that Samantha must be taken. (4x23 Demons)
November 27, 1973
Samantha Mulder and Cassandra Spender both disappear.
Cassandra Spender, wife of C.G.B. Spender, is later confirmed to have been kidnapped repeatedly by the government conspiracy, working to make her a human-alien hybrid. C.G.B. Spender is later determined to be an alias of the Cigarette Smoking Man. (6x11 Two Fathers)
Samantha is taken just as her older brother, Fox, is getting ready to watch his favorite TV program, their parents are next door, visiting the Galbrands. (2x01 Little Green Men)
Samantha ends up in the care of C.G.B. Spender and she lives with his family in residential quarters on the April Air Force Base in California. Jeffrey Spender is apparently living with the family, as well. (7x11 Closure) 
1974
Government sponsored testing of radiation treatment on civilians ends, Dr. Zama continues his experimentation in West Virginia. (3x09 Nisei & 3x10 731)
Circa 1975
According to the Bounty Hunter, posing as CIA agent Ambrose Chapel, around the mid-1970s, several of the Soviet "Gregor" clones enters the United States to infiltrate the medical industry to be ready to commit sabotage in the time of war. (Colony / End Game)
1976
Darius Michaud joins the FBI. (Fight the Future)
1977
Cassandra Spender is involved in a UFO cult. (5x13 Patient X)
John Doggett enters the Marine Corp, he becomes part of the USMC 24th Marine Amphibious Unit. (8x01 Within)
August 2, 1977
Two Voyager spacecraft are launched from the Kennedy Space Flight Center in Florida. Each carries a gold recording with many messages from mankind. (2x01 Little Green Men)
August 1977
A researcher working with the Ohio State University finds data on a signal received that was thirty times stronger than the galactic background, he is so impressed that he writes "WOW" on the printout. (2x01 Little Green Men) 
1978
The Bounty Hunter, posing as Ambrose Chapel, claimed to have a 17 year career with the CIA, meaning he would have joined the organization in 1978. (2x16 Colony and 2x17 End Game)
June 13, 1978
Morris and Joanne Fletcher are married. He soon becomes a "man in black" working at Area 51 to mislead the American public about the existence of aliens. (6x05 Dreamland II)
February 23, 1979
On Dana's fifteenth birthday, Margaret Scully gives her daughter a necklace consisting of a gold cross on a gold chain. (2x06 Ascension)
October 23, 1979
Unable to stand the tests any longer, Samantha Mulder, age 14, runs away from the Spender home at April Air Force Base in California. She believes that those performing the tests have taken her memories -- she has only vague memories of a brother. (7x10 Closure) 
May 1980
Fox Mulder graduates from High School.
December 26, 27 and 28, 1980
Several UFO sightings occurred at Rendlesham Forest at Suffolk, Great Brittan on three consecutive nights. The area was rumored to be owned by the NSA and the incidents occurred on US airbases. The incidents have the highest number of Military and Civilian eyes witnesses after Roswell from 1947. (Historical / UFO research) 
1982
FBI agent Duane Barry is shot in the head. He survives, but has severe mental problems for the rest of his life. His wife and family leave him. (2x05 Duane Barry)
Sergeant John Doggett, USMC, begins service with the Multi-national peacekeeping force in Lebanon. (8x01 Within)
Fall 1982
Dana Scully enters college, receiving an undergraduate degree in physics from the University of Maryland.
1983
Eve 6 is incarcerated in the Whiting Institute for the Criminally Insane, She claims to be the continuing subject of tests under the Litchfield Experiment. (1x11 Eve) 
Fox Mulder enters college.
October 30, 1983
Sergeant John Doggett, USMC, concludes his tour of service with the Multi-national peacekeeping force in Lebanon. (8x01 Within)
1985
Sergeant John Doggett separates from the US Marine Corp, at a pay grade of E-5, after approximately 18 years of service.
Sally Kendrick, AKA Eve 7, goes to work for the Luther Stape Center for Reproductive Medicine in San Francisco. (1x11 Eve) 
1986
Fox Mulder completes his Oxford degree in Psychology.
Mulder is given the FBI badge number 22791. (7x08 The Amazing Maleeni)
Sometime in 1986 Gibson Praise is born. (5x20 The End)
May 15, 1986
The date on Scully's senior thesis, at the University of Maryland, "Einstein's Twin Paradox: A New Interpretation." (4x07 Musings of a Cigarette Smoking Man)
Mulder graduates at the top of his 15-week class at the Quantico FBI academy, earning the nickname "Spooky."
1986
Mulder's initial FBI assignment is apparently as a "general assignment" agent.
1987
John Doggett joins the New York City Police Department as a detective in the Fugative Unit. (8x01 Within)
According to Deep Throat, a group of school children from a southern state is injected with cloned alien DNA without their parent's knowledge. (1x23 The Erlenmeyer Flask)
1988
Members of the high school class of 1989 of Bellefleur, Oregon, begin suffering a series of unexplained disappearances and deaths. Others suffer from what appears to post traumatic stress syndrome. (1x79 Pilot)
Late 1988
Mulder is assigned to the violent crimes section, where he is generally considered to be an expert analyst.
Mulder is partnered with Jerry Lamana in the Violent Crimes unit. (1x06 Ghost in the Machine)
1988 or 89
Mulder is stationed in Washington DC.
At this time he rents apartment 42 at 2639 Hegal Place, Alexandria, Virginia, and acquires the telephone number (202) 555-0110. (8x01 Within)
May 1989
The trio of paranoid conspiracy theorists known as The Lone Gunmen, meet and begin working together, this also marks Mulder's first encounter with them.
June 16, 1989
Mulder works with Dr. Heitz Werber to use regression therapy to remember the night his sister disappeared. 
Late 1980s or early 1990s
Dana Scully's nephew is born. (4x03 Home)
1990s
At some point, described only as "several years" before 1997, a forensic anthropologist named Arlinsky is implicated in a UFO photo enhancement scandal. (4x24 Gethsemane)
Estimated; A team of Russian geologists locates rock from the Tunguska meteorite, the rock contains an organism, probably extraterrestrial in origin, that invades human bodies.
The Russian government may have sent Alex Krycek to America as a mole to infiltrate the Conspiracy with the ultimate plan of ending Conspiracy Black Cancer research. (4x10 Terma) 
1990
At least two pilots at Ellens AFB begin acting strangely in a way Scully later says is typical of reaction to extreme stress. (1x01 Deep Throat)
The American Voyager 1 spacecraft crosses the orbit of Neptune, effectively leaving the solar system. (2x01 Little Green Men)
Dana Scully completes medical training. The FBI recruits her during final months of her residency and she enrolls in the 15-week FBI Academy training course.
Spring 1990
Scully graduates from the 15-week new agent course at the FBI Academy, and is presently assigned to teach at the Academy, because of her medical degree.
November 17, 1990
Fox Mulder interviews former FBI agent Arthur Dale who opened an X-Files on Edward Skur in 1952. (5x15 Travelers)
Late 1990 or Early 1991
Mulder's success in violent crimes allows him a certain latitude to pursue his own interests, he discovers the X-Files. (1x79 Pilot)
1991
The Simmons family moves from San Francisco to Greenwich, Connecticut, including their five year old daughter Tina, who is actually an Eve clone. (1x11 Eve.)
Scully's former playmate, Richard Johansen, is killed in a training accident during the Gulf War. (3x09 Nisei & 3x10 731)
Michael Kritschgau claims in 1997 that his son, Michael Jr., is very ill as the result of Conspiracy chemical warfare experiments during the Gulf War. (4x24 Gethsemane and 5x02 Redux)
Militia member Timothy Edward Mayhew, tells Scully and Mulder in 1996 that the "Black Cancer" was used as biological warfare during the Gulf War. (4x10 Terma)
Supersoldiers fight during the Gulf War. (9x11 Providence)
Circa 1991
Zeus Storage, somewhere in the Washington DC area, is where the first DNA transplant is made, and the first human/alien hybrid created, with six terminally ill human subjects volunteering. Dr. William Sakar recovers as the result of ET gene therapy, developing inhuman strength and the ability to breath under water and green caustic blood. (1x23 The Erlenmeyer Flask) 
February 26, 1991
During the Gulf War, a recon suad lead by Josepho is ambushed and takes heavy casualties. Josepho's squad is actually saved by a team of supersoldiers. (9x11 Providence) 
December 1991
Mulder receives the assignment he has desired since joining the FBI, The X-Files, ending his partnership with Lamana. The assignment is effective in January. (4x07 Musings of a Cigarette Smoking Man)
One of his first actions is to open an X-File on his missing sister. (1x03 Conduit)
December 24, 1991
At Dogway, West Virginia, a UFO crashes, and a critically injured EBE is recovered by the UFO recovery team working for Deep Throat. The EBE is placed in an intensive care unit. Deep Throat unwillingly executes the EBE, citing Security Council Resolution 1013, stating that any country capturing an EBE is responsible for its immediate extermination. (4x07 Musings of a Cigarette Smoking Man / 1x16 E.B.E.) 
February 1992
Mulder's work attracts the attention of the Conspiracy. They look for a way to reign Mulder in without making him a martyr. He tries to access certain information, but is blocked by higher offices. (1x79 Pilot)
NICAP, the National Investigation Committee on Aerial Phenomenon, begins following the work of Agent Mulder. Using the Freedom of Information Act, NICAP obtains Mulder's travel vouchers, to track his investigations. (1x09 Fallen Angel)
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Historical Introduction
Prehistory to 1970
1970 to 1992
1992 to 1994
1994 to 1995
1995 to 1996
1996 to 1997
1997 to 1998
1998 to 1999
1999 to 2000
2000 to 2001
2001 to 2002